The Red Sox will use much the same lineup against Jeremy Guthrie Wednesday as they did against Zach Britton, with the only difference coming from J.D. Drew and Jed Lowrie switching places against the right-handed picher.
1. Jacoby Ellsbury, CF
2. Dustin Pedroia, 2B
3. Adrian Gonzalez, 1B
4. Kevin Youkilis, 3B
5. David Ortiz, DH
6. J.D. Drew, RF
7. Jed Lowrie, SS
8. Carl Crawford, LF
9. Jason Varitek, C
--Josh Beckett, SP
Jason Varitek will, to nobody's great surprise, get the start behind the plate with Josh Beckett on the mound.
The Orioles will respond with:
1. Brian Roberts, 2B
2. Nick Markakis, RF
3. Derrek Lee, 1B
4. Vlad Guerrero, DH
5. Luke Scott, LF
6. Adam Jones, CF
7. Mark Reynolds, 3B
8. Matt Wieters, C
9. Robert Andino, SS
-- Jeremy Guthrie, SP