After taking advantage of many Buffalo mistakes in the game's opening quarter, the New England Patriots took a 10-0 lead into the second. However, the Bills were in the midst of a successful drive and had control of the ball inside Patriots' territory.
However, a Rob Ninkovich sack would stop the bills in their tracks and force a Rian Lindell field goal attempt. His kick was right down the middle, cutting the Patriots' lead to 10-3.
On their next drive, the Patriots would make like a hot knife through butter, exploiting the Buffalo defense on each and every play. They would cap off the drive with a 15-yard touchdown run by reserve tailback Danny Woodhead as he followed the left side of the offensive line into a gaping hole in the defense. This score would put New England ahead, 17-3.
Much to the display of the 67,000-plus on hand at Gillette Stadium, the Bills would return the favor, moving the ball down the field with ease. The drive would finish on a bruising touchdown run by Fred Jackson to cut the Bills' deficit to 17-10.
Another costly penalty against the Bills would be called on rookie cornerback Stephon Gilmore for pass interference in the end-zone, once again setting up the Patriots inside the one-yard-line. Tom Brady would connect with tight end Rob Gronkowski for the short touchdown pass to give the Patriots a 24-10 lead.
Buffalo's two-minute drill would turn out to be just as effective as their normal offense, marching right back down into Patriots territory for a late score. It would be tight end Scott Chandler who would catch a short touchdown pass from Ryan Fitzpatrick to cut the deficit to 24-17.
Despite the offense playing well in the first half, the Patriots find themselves in a tight game with an inferior team due to constant struggles on defense.