The New England Patriots, one of the league's final three one-loss teams and winners of three straight, head west to San Diego to battle the Chargers is a matchup of recently traditional AFC powers.
The Chargers opened as a three-point favorite, with the O/U set at 49 points. New England last faced San Diego in Week 6 in 2008, with the Chargers coming out on top, 30-10. The Pats were winners twice in 2007, including a 21-12 victory in the AFC Championship Game.