New England and St. Louis meet in London, where the Patriots will be the clear-cut favorites.
SB Nation's Ryan Van Bibber, in predicting a 23-14 New England win, said, "Tom Brady and the Patriots are favored by a touchdown in the eyes of most sports books, but the Rams are 5-2 against the spread thanks to a solid defense.
"The problem the Rams have is that it takes a Herculean effort to score 20 points. The Patriots don't have that problem."
Peter King of Sports Illustrated foresees a 30-20 Patriots win and doesn't think the world travel will impact Brady and the offensive attack.